Indian Scientists Develop Gold Nano-Cups for Advanced Cancer Therapy
| Aspect | Details |
|---|---|
| Event | Indian scientists develop gold nano-cups for cancer treatment |
| Date | June 17, 2025 |
| Reported by | Press Information Bureau (PIB) |
| Published in | Communications Chemistry (Nature group journal) |
| Developed by | INST Mohali (DST), IIT Bombay, and ACTREC - Tata Memorial Centre |
| Key Innovation | One-step colloidal synthesis of PEGylated semi-shells using ZIF-8 MOF template |
| Method | ZIF-8 crystals etched with ascorbic acid; gold nanoparticles form nano-cup structures |
| Function | Absorbs near-infrared (NIR) light, converts it into heat to destroy tumor cells |
| Objective | Provide minimally invasive, heat-based cancer treatment |
| Biocompatibility | Uses non-toxic agents (e.g., Vitamin C) |
| Therapeutic Efficacy | Destroys metastatic breast tumors in animal models with high precision and minimal relapse |
| Significance | Replaces toxic, multi-step, high-temperature methods; enhances advanced oncological treatments |